3HOM

Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acidic fibroblast growth factor	polymer	146	16718.8	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Heparin-binding growth factor 1, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A, B	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Cys 66	Ala 81	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33437.6
Non-Polymers*	Number of molecules	3
	Total formula weight	188.1
All*	Total formula weight	33625.7

*Water molecules are not included.