3HOM
Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acidic fibroblast growth factor | polymer | 146 | 16718.8 | 2 | UniProt (P05230) Pfam (PF00167) | Homo sapiens (human) | HBGF-1, Heparin-binding growth factor 1, aFGF, Beta-endothelial cell growth factor, ECGF-beta |
| 2 | C, E (A, B) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
| PDB | External Database | Details |
|---|---|---|
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| Cys 66 | Ala 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33437.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 188.1 | |
| All* | Total formula weight | 33625.7 |
