3H8K
Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution
Summary for 3H8K
Entry DOI | 10.2210/pdb3h8k/pdb |
Related | 2CYX 3FSH |
Descriptor | Ubiquitin-conjugating enzyme E2 G2, Autocrine motility factor receptor, isoform 2 (3 entities in total) |
Functional Keywords | alpha beta, all alpha, ligase, ubl conjugation pathway, endoplasmic reticulum, membrane, metal-binding, phosphoprotein, receptor, transmembrane, zinc-finger |
Biological source | Homo sapiens (human) More |
Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q9UKV5 |
Total number of polymer chains | 2 |
Total formula weight | 22003.18 |
Authors | Kalathur, R.C.,Das, R.,Li, J.,Byrd, R.A.,Ji, X. (deposition date: 2009-04-29, release date: 2009-07-14, Last modification date: 2023-09-06) |
Primary citation | Das, R.,Mariano, J.,Tsai, Y.C.,Kalathur, R.C.,Kostova, Z.,Li, J.,Tarasov, S.G.,McFeeters, R.L.,Altieri, A.S.,Ji, X.,Byrd, R.A.,Weissman, A.M. Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78. Mol.Cell, 34:674-685, 2009 Cited by PubMed: 19560420DOI: 10.1016/j.molcel.2009.05.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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