3H11
Zymogen caspase-8:c-FLIPL protease domain complex
Summary for 3H11
Entry DOI | 10.2210/pdb3h11/pdb |
Related | 3H13 |
Descriptor | CASP8 and FADD-like apoptosis regulator, Caspase-8, IETD aldehyde inhibitor, ... (4 entities in total) |
Functional Keywords | cell death, apoptosis, caspase, alternative splicing, host-virus interaction, polymorphism, cytoplasm, disease mutation, hydrolase, phosphoprotein, protease, thiol protease, zymogen |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q14790 |
Total number of polymer chains | 3 |
Total formula weight | 62982.91 |
Authors | Jeffrey, P.D.,Yu, J.W.,Shi, Y. (deposition date: 2009-04-10, release date: 2009-04-28, Last modification date: 2021-10-13) |
Primary citation | Yu, J.W.,Jeffrey, P.D.,Shi, Y. Mechanism of procaspase-8 activation by c-FLIPL. Proc.Natl.Acad.Sci.USA, 106:8169-8174, 2009 Cited by PubMed: 19416807DOI: 10.1073/pnas.0812453106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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