3GN4

Myosin lever arm

Summary for 3GN4

• Entry DOI: 10.2210/pdb3gn4/pdb
• Descriptor: Myosin-VI, Calmodulin, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: unconventional myosin, motility, lever arm, 3-helix bundle, actin-binding, atp-binding, calmodulin-binding, coiled coil, cytoplasm, endocytosis, golgi apparatus, hearing, membrane, motor protein, myosin, nucleotide-binding, nucleus, phosphoprotein, protein transport, transport, acetylation, calcium, motor protein-metal binding protein complex
• Biological source: Sus scrofa (pig); More
• Cellular location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein (By similarity): Q29122
• Total number of polymer chains: 6
• Total formula weight: 102513.10

Authors

Mukherjea, M.,Llinas, P.,Kim, H.,Travaglia, M.,Safer, D.,Zong, A.B.,Menetrey, J.,Franzini-Armstrong, C.,Selvin, P.R.,Houdusse, A.,Sweeney, H.L. (deposition date: 2009-03-16, release date: 2009-09-08, Last modification date: 2023-09-06)

• Primary citation: Mukherjea, M.,Llinas, P.,Kim, H.,Travaglia, M.,Safer, D.,Menetrey, J.,Franzini-Armstrong, C.,Selvin, P.R.,Houdusse, A.,Sweeney, H.L.; Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach; Mol.Cell, 35:305-315, 2009; PubMed: 19664948; DOI: 10.1016/j.molcel.2009.07.010

Experimental method

X-RAY DIFFRACTION (2.7 Å)