3GDX
Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP
Summary for 3GDX
Entry DOI | 10.2210/pdb3gdx/pdb |
Related | 2FMS |
Descriptor | DNA polymerase beta, 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ... (9 entities in total) |
Functional Keywords | nucloetidyl transferase, dna polymerase, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, nucleotidyltransferase, nucleus, polymorphism, sodium, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 47314.28 |
Authors | Wilson, S.H.,Batra, V.K.,Pedersen, L.C. (deposition date: 2009-02-24, release date: 2009-05-05, Last modification date: 2023-09-06) |
Primary citation | Upton, T.G.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Prakash, G.K.,Kultyshev, R.,Batra, V.K.,Shock, D.D.,Pedersen, L.C.,Beard, W.A.,Wilson, S.H. Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function Org.Lett., 11:1883-1886, 2009 Cited by PubMed: 19351147DOI: 10.1021/ol701755k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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