3FX0

Crystal structure of Human NEMO CC2_LZ domain

Summary for 3FX0

• Entry DOI: 10.2210/pdb3fx0/pdb
• Descriptor: NF-kappa-B essential modulator (1 entity in total)
• Functional Keywords: coiled-coil, coiled coil, cytoplasm, disease mutation, ectodermal dysplasia, host-virus interaction, metal-binding, nucleus, osteopetrosis, phosphoprotein, transcription, transcription regulation, ubl conjugation, zinc, zinc-finger, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q9Y6K9
• Total number of polymer chains: 2
• Total formula weight: 22149.24

Authors

Lo, Y.C.,Lin, S.C.,Wu, H. (deposition date: 2009-01-19, release date: 2009-04-07, Last modification date: 2024-02-21)

• Primary citation: Lo, Y.C.,Lin, S.C.,Rospigliosi, C.C.,Conze, D.B.,Wu, C.J.,Ashwell, J.D.,Eliezer, D.,Wu, H.; Structural basis for recognition of diubiquitins by NEMO.; Mol.Cell, 33:602-615, 2009; PubMed: 19185524; DOI: 10.1016/j.molcel.2009.01.012

Experimental method

X-RAY DIFFRACTION (3.2 Å)