3FP7

Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit

Summary for 3FP7

Entry DOI	10.2210/pdb3fp7/pdb
Related	3FP6 3FP8 3TGI
Descriptor	Anionic trypsin-2, Pancreatic trypsin inhibitor, 1,2-ETHANEDIOL, ... (8 entities in total)
Functional Keywords	enzyme-inhibitor complex, peptide bond hydrolysis, calcium, digestion, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, pharmaceutical, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Rattus norvegicus (brown rat,rat,rats) More
Cellular location	Secreted, extracellular space: P00763 Secreted: P00974 P00974
Total number of polymer chains	3
Total formula weight	31273.32
Authors	Zakharova, E.,Horvath, M.P.,Goldenberg, D.P. (deposition date: 2009-01-04, release date: 2009-02-17, Last modification date: 2023-09-06)
Primary citation	Zakharova, E.,Horvath, M.P.,Goldenberg, D.P. Structure of a serine protease poised to resynthesize a peptide bond. Proc.Natl.Acad.Sci.USA, 106:11034-11039, 2009 Cited by PubMed: 19549826 DOI: 10.1073/pnas.0902463106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation