3FP7
Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Anionic trypsin-2 | polymer | 223 | 23798.8 | 1 | UniProt (P00763) Pfam (PF00089) | Rattus norvegicus (brown rat rat rats) | Anionic trypsin II, Pretrypsinogen II, Serine protease 2 |
| 2 | B (I) | Pancreatic trypsin inhibitor | polymer | 15 | 1725.0 | 1 | UniProt (P00974) | Basic protease inhibitor, BPTI, BPI, Aprotinin | |
| 3 | C (J) | Pancreatic trypsin inhibitor | polymer | 43 | 4820.6 | 1 | UniProt (P00974) Pfam (PF00014) | Basic protease inhibitor, BPTI, BPI, Aprotinin | |
| 4 | D, E, F, G, J (E, I) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | H (E) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | I (E) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | K, L, M, N (J) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 8 | O, P, Q (E, I, J) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
E: 16 - 245 (UniProt: P00763)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30344.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 928.9 | |
| All* | Total formula weight | 31273.3 |
