3FM7

Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain

Summary for 3FM7

Entry DOI	10.2210/pdb3fm7/pdb
Descriptor	Dynein light chain Tctex-type, Dynein intermediate chain, cytosolic, Dynein light chain 1, cytoplasmic (3 entities in total)
Functional Keywords	cytoplasmic dynein, light chain tctex-1, tctex, light chain 8, lc8, intermediate chain, ic, dynein cargo attachment complex, dynein light chain, quaternary structure, dynein, microtubule, motor protein, lysosome, membrane, nucleus, wd repeat, contractile protein
Biological source	Drosophila melanogaster (Fruit fly) More
Cellular location	Cytoplasm, cytoskeleton (Probable): Q94524 Cytoplasm, cytoskeleton. Isoform 2c: Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2a: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2b: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side: Q24246 Cytoplasm, cytoskeleton: Q24117
Total number of polymer chains	6
Total formula weight	51868.55
Authors	Hall, J.D.,Karplus, P.A.,Barbar, E.J. (deposition date: 2008-12-19, release date: 2009-09-15, Last modification date: 2023-09-06)
Primary citation	Hall, J.,Karplus, P.A.,Barbar, E. Multivalency in the assembly of intrinsically disordered Dynein intermediate chain. J.Biol.Chem., 284:33115-33121, 2009 Cited by PubMed: 19759397 DOI: 10.1074/jbc.M109.048587 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation