3FL0
X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Summary for 3FL0
Entry DOI | 10.2210/pdb3fl0/pdb |
Related | 1A2W 1BSR 1H8X 1TQ9 3BCP 3FKZ 3FL1 3FL3 |
Descriptor | Ribonuclease pancreatic, 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | 3d-domain swapping, bovine seminal ribonuclease, non-covalent dimer, antitumor activity, quaternary structure flexibility, protein mutations and evolution, endonuclease, glycation, glycoprotein, hydrolase, nuclease, secreted |
Biological source | Bos taurus (Bovine) |
Cellular location | Secreted: P61823 |
Total number of polymer chains | 2 |
Total formula weight | 28151.39 |
Authors | Merlino, A.,Russo Krauss, I.,Perillo, M.,Mattia, C.A.,Ercole, C.,Picone, D.,Vergara, A.,Sica, F. (deposition date: 2008-12-18, release date: 2009-03-24, Last modification date: 2023-11-01) |
Primary citation | Merlino, A.,Russo Krauss, I.,Perillo, M.,Mattia, C.A.,Ercole, C.,Picone, D.,Vergara, A.,Sica, F. Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants Biopolymers, 91:1029-1037, 2009 Cited by PubMed: 19280639DOI: 10.1002/bip.21183 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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