3FJZ

E. coli EPSP synthase (T97I) liganded with S3P and glyphosate

Summary for 3FJZ

• Entry DOI: 10.2210/pdb3fjz/pdb
• Related: 1g6t 2qft 3FJX 3FK0 3FK1
• Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, SERINE, N-(phosphonomethyl)glycine, ... (6 entities in total)
• Functional Keywords: inside-out alpha-beta barrel, amino-acid biosynthesis, aromatic amino acid biosynthesis, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm (Probable): P0A6D3
• Total number of polymer chains: 1
• Total formula weight: 47050.16

Authors

Schonbrunn, E. (deposition date: 2008-12-15, release date: 2009-02-17, Last modification date: 2023-09-06)

• Primary citation: Funke, T.,Yang, Y.,Han, H.,Healy-Fried, M.,Olesen, S.,Becker, A.,Schonbrunn, E.; Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.; J.Biol.Chem., 284:9854-9860, 2009; PubMed: 19211556; DOI: 10.1074/jbc.M809771200

Experimental method

X-RAY DIFFRACTION (1.7 Å)