3FEP

Crystal structure of the R132K:R111L:L121E:R59W-CRABPII mutant complexed with a synthetic ligand (merocyanin) at 2.60 angstrom resolution.

Summary for 3FEP

Entry DOI	10.2210/pdb3fep/pdb
Related	2fr3 2fs6 2g7b 3FEK 3FEL 3FEN 3f8a
Descriptor	Cellular retinoic acid-binding protein 2, (2E,4E,6E)-3-methyl-6-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)hexa-2,4-dienal, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	merocyanin, crabpii, retinoic acid, retinoid, psb, protonated schiff base, fluorescence, crabp, nucleus, retinol-binding, transport, vitamin a, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	16017.33
Authors	Jia, X.,Geiger, J.H. (deposition date: 2008-11-30, release date: 2009-11-10, Last modification date: 2023-09-06)
Primary citation	Yapici, I.,Lee, K.S.,Berbasova, T.,Nosrati, M.,Jia, X.,Vasileiou, C.,Wang, W.,Santos, E.M.,Geiger, J.H.,Borhan, B. "Turn-on" protein fluorescence: in situ formation of cyanine dyes. J.Am.Chem.Soc., 137:1073-1080, 2015 Cited by PubMed: 25534273 DOI: 10.1021/ja506376j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation