3FA6
Crystal structure of the R132K:Y134F:R111L:L121D:T54V mutant of cellular retinoic acid-binding protein II complexed with C15-aldehyde (a retinal analog) at 1.54 angstrom resolution
Summary for 3FA6
Entry DOI | 10.2210/pdb3fa6/pdb |
Related | 3CR6 3F8A 3F9D 3FA7 3FA8 3FA9 |
Descriptor | Cellular retinoic acid-binding protein 2, 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene (3 entities in total) |
Functional Keywords | crabpii, retinal, protonated schiff base, psb, c15-aldehyde, retinoic acid, retinoid, cytoplasm, nucleus, retinol-binding, transport, vitamin a, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P29373 |
Total number of polymer chains | 2 |
Total formula weight | 31396.12 |
Authors | Jia, X.,Geiger, J.H. (deposition date: 2008-11-15, release date: 2009-10-27, Last modification date: 2023-12-27) |
Primary citation | Jia, X.,Lee, K.S.,Vasileiou, C.,Borhan, B.,Geiger, J.H. Two distinctive orientations of binding determined by a single mutation in the CRABPII mutant-C15-aldehyde complexes To be Published, |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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