3F8U

Tapasin/ERp57 heterodimer

Summary for 3F8U

Entry DOI	10.2210/pdb3f8u/pdb
Descriptor	Protein disulfide-isomerase A3ERp57, Tapasin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	endoplasmic reticulum, glycoprotein, immunoglobulin domain, membrane, microsome, protein disulfide isomerase, thioredoxin-like fold, ig-like domain, beta barrel, isomerase, redox-active cente, immune system-isomerase complex, immune system/isomerase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	194628.14
Authors	Dong, G.,Reinisch, K.M. (deposition date: 2008-11-13, release date: 2009-01-13, Last modification date: 2023-12-27)
Primary citation	Dong, G.,Wearsch, P.A.,Peaper, D.R.,Cresswell, P.,Reinisch, K.M. Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer. Immunity, 30:21-32, 2009 Cited by PubMed: 19119025 DOI: 10.1016/j.immuni.2008.10.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation