3EXX

Structure of the T6 human insulin derivative with nickel at 1.35 A resolution

Summary for 3EXX
DescriptorInsulin A chain, Insulin B chain, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordsnickel insulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight11798.67
Authors
Prugovecki, B.,Matkovic-Calogovic, D. (deposition date: 2008-10-17, release date: 2009-05-19, Last modification date: 2011-09-07)
Primary citationDodson, E.,Dodson, G.,Matkovic-Calogovic, D.,Prugovecki, B.
Structure of the T6 Human Nickel Insulin Derivative at 1.35 A Resolution.
CROATICA CHEMICA ACTA, 82:433-438, 2009
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation
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PDB entries from 2021-06-23