3ETB
Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4
Summary for 3ETB
Entry DOI | 10.2210/pdb3etb/pdb |
Related | 3ESU 3ESV 3ET9 |
Descriptor | Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker, Anthrax Protective Antigen (2 entities in total) |
Functional Keywords | single-chain fv, monoclonal antibody, immunoglobulin, toxin, antibody-antigen complex, immune system-toxin complex, immune system/toxin |
Biological source | Mus musculus (mouse) More |
Cellular location | Secreted, extracellular space: P13423 |
Total number of polymer chains | 8 |
Total formula weight | 173464.69 |
Authors | Monzingo, A.F.,Leysath, C.E.,Barnett, J.,Iverson, B.L.,Georgiou, G.,Robertus, J.D. (deposition date: 2008-10-07, release date: 2009-04-28, Last modification date: 2023-09-06) |
Primary citation | Leysath, C.E.,Monzingo, A.F.,Maynard, J.A.,Barnett, J.,Georgiou, G.,Iverson, B.L.,Robertus, J.D. Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. J.Mol.Biol., 387:680-693, 2009 Cited by PubMed: 19361425DOI: 10.1016/j.jmb.2009.02.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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