3EIQ
Crystal structure of Pdcd4-eIF4A
Summary for 3EIQ
Entry DOI | 10.2210/pdb3eiq/pdb |
Descriptor | Eukaryotic initiation factor 4A-I, Programmed cell death protein 4 (2 entities in total) |
Functional Keywords | pdcd4, anti-oncogene, apoptosis, cell cycle, nucleus, phosphoprotein, rna-binding, atp-binding, helicase, hydrolase, initiation factor, nucleotide-binding, protein biosynthesis, antitumor protein, translation, hydrolase-antitumor protein complex, hydrolase/antitumor protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P60842 |
Total number of polymer chains | 3 |
Total formula weight | 133827.52 |
Authors | |
Primary citation | Loh, P.G.,Yang, H.S.,Walsh, M.A.,Wang, Q.,Wang, X.,Cheng, Z.,Liu, D.,Song, H. Structural basis for translational inhibition by the tumour suppressor Pdcd4 Embo J., 28:274-285, 2009 Cited by PubMed: 19153607DOI: 10.1038/emboj.2008.278 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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