3EB6

Structure of the cIAP2 RING domain bound to UbcH5b

Summary for 3EB6

• Entry DOI: 10.2210/pdb3eb6/pdb
• Related: 3EB5
• Descriptor: Baculoviral IAP repeat-containing protein 3, Ubiquitin-conjugating enzyme E2 D2, ZINC ION (3 entities in total)
• Functional Keywords: ring domain, e2, apoptosis, metal-binding, zinc-finger, ligase, ubl conjugation pathway
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Potential): Q13489
• Total number of polymer chains: 2
• Total formula weight: 25268.85

Authors

Mace, P.D.,Linke, K.,Schumacher, F.-R.,Smith, C.A.,Day, C.L. (deposition date: 2008-08-27, release date: 2008-09-09, Last modification date: 2024-02-21)

• Primary citation: Mace, P.D.,Linke, K.,Feltham, R.,Schumacher, F.R.,Smith, C.A.,Vaux, D.L.,Silke, J.,Day, C.L.; Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment.; J.Biol.Chem., 283:31633-31640, 2008; PubMed: 18784070; DOI: 10.1074/jbc.M804753200

Experimental method

X-RAY DIFFRACTION (3.4 Å)