3E93
Crystal Structure of P38 Kinase in Complex with A Biaryl Amide Inhibitor
Summary for 3E93
Entry DOI | 10.2210/pdb3e93/pdb |
Related | 3E92 |
Descriptor | Mitogen-activated protein kinase 14, 4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | p38, serine/threonine protein kinase, map kinase, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43439.62 |
Authors | Somers, D.O.,Patel, S. (deposition date: 2008-08-21, release date: 2008-09-30, Last modification date: 2023-11-15) |
Primary citation | Baldwin, I.,Bamborough, P.,Haslam, C.G.,Hunjan, S.S.,Longstaff, T.,Mooney, C.J.,Patel, S.,Quinn, J.,Somers, D.O. Kinase array design, back to front: Biaryl amides Bioorg.Med.Chem.Lett., 18:5285-5289, 2008 Cited by PubMed: 18789685DOI: 10.1016/j.bmcl.2008.08.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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