3E68
Structure of murine INOS oxygenase domain with inhibitor AR-C130232
Summary for 3E68
Entry DOI | 10.2210/pdb3e68/pdb |
Related | 3E65 3E67 |
Descriptor | Nitric oxide synthase, inducible, octyl beta-D-glucopyranoside, SULFATE ION, ... (8 entities in total) |
Functional Keywords | nitric oxide, nos, heme, tetrahydrobiopterin, oxidoreductase, calmodulin-binding, fad, fmn, iron, metal-binding, nadp, polymorphism, zinc |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 103955.48 |
Authors | Garcin, E.D.,Arvai, A.S.,Rosenfeld, R.J.,Kroeger, M.D.,Crane, B.R.,Andersson, G.,Andrews, G.,Hamley, P.J.,Mallinder, P.R.,Nicholls, D.J.,St-Gallay, S.A.,Tinker, A.C.,Gensmantel, N.P.,Mete, A.,Cheshire, D.R.,Connolly, S.,Stueh, D.J.,Aberg, A.,Wallace, A.V.,Tainer, J.A.,Getzoff, E.D. (deposition date: 2008-08-14, release date: 2008-10-07, Last modification date: 2024-02-21) |
Primary citation | Garcin, E.D.,Arvai, A.S.,Rosenfeld, R.J.,Kroeger, M.D.,Crane, B.R.,Andersson, G.,Andrews, G.,Hamley, P.J.,Mallinder, P.R.,Nicholls, D.J.,St-Gallay, S.A.,Tinker, A.C.,Gensmantel, N.P.,Mete, A.,Cheshire, D.R.,Connolly, S.,Stuehr, D.J.,Aberg, A.,Wallace, A.V.,Tainer, J.A.,Getzoff, E.D. Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4:700-707, 2008 Cited by PubMed: 18849972DOI: 10.1038/nchembio.115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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