3DD3
Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta
Summary for 3DD3
Entry DOI | 10.2210/pdb3dd3/pdb |
Descriptor | Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, (eta6-benzene)ruthenium, ... (5 entities in total) |
Functional Keywords | transferase, glutathione, detoxification, etharapta, ruthenium, rapta-c, ethacrynic-acid |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 47939.84 |
Authors | Parker, L.J. (deposition date: 2008-06-05, release date: 2009-04-21, Last modification date: 2023-11-01) |
Primary citation | Ang, W.H.,Parker, L.J.,De Luca, A.,Juillerat-Jeanneret, L.,Morton, C.J.,Lo Bello, M.,Parker, M.W.,Dyson, P.J. Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48:3854-3857, 2009 Cited by PubMed: 19396894DOI: 10.1002/anie.200900185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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