3D91

Human renin in complex with remikiren

Summary for 3D91

• Entry DOI: 10.2210/pdb3d91/pdb
• Descriptor: Renin, Nalpha-[(2S)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-L-histidinamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: renin, remikiren, alternative splicing, aspartyl protease, cleavage on pair of basic residues, disease mutation, glycoprotein, hydrolase, membrane, polymorphism, protease, secreted, zymogen
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P00797
• Total number of polymer chains: 2
• Total formula weight: 76228.25

Authors

Prade, L.,Bezencon, O.,Bur, D.,Weller, T.,Fischli, W.,Remen, L. (deposition date: 2008-05-26, release date: 2008-06-17, Last modification date: 2011-07-13)

• Primary citation: Prade, L.,Bezencon, O.,Bur, D.,Weller, T.,Fischli, W.,Remen, L.; Human renin in complex with remikiren; to be published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)