Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE REM A 350 |
| Chain | Residue |
| A | GLN19 |
| A | ALA229 |
| A | SER230 |
| A | SER233 |
| A | HIS301 |
| A | MET303 |
| A | ALA314 |
| A | ASP38 |
| A | GLY40 |
| A | TYR83 |
| A | SER84 |
| A | THR85 |
| A | PHE124 |
| A | ASP226 |
| A | GLY228 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE REM B 350 |
| Chain | Residue |
| B | GLN19 |
| B | ASP38 |
| B | TYR83 |
| B | SER84 |
| B | THR85 |
| B | PRO118 |
| B | ASP226 |
| B | GLY228 |
| B | ALA229 |
| B | SER230 |
| B | SER233 |
| B | HIS301 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 351 |
| Chain | Residue |
| A | THR18 |
| A | GLN19 |
| A | TYR20 |
| A | THR227 |
| A | GLY228 |
| A | ALA229 |
| A | SER230 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 351 |
| Chain | Residue |
| B | THR18 |
| B | GLN19 |
| B | TYR20 |
| B | GLY228 |
| B | SER230 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV |
| Chain | Residue | Details |
| A | VAL35-VAL46 | |
| A | ALA223-GLY234 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20927107","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2493678","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP226 | |
| A | THR39 | |
| A | THR227 | |
| site_id | CSA10 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP226 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP38 | |
| B | ASP226 | |
| B | THR39 | |
| B | THR227 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP226 | |
| A | SER41 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP38 | |
| B | ASP226 | |
| B | SER41 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP226 | |
| A | TYR83 | |
| A | SER41 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP38 | |
| B | ASP226 | |
| B | TYR83 | |
| B | SER41 | |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP38 | |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP38 | |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP226 | |
