3D6C

Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature

Summary for 3D6C

Entry DOI	10.2210/pdb3d6c/pdb
Descriptor	Thermonuclease, CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	staphylococcal nuclease, hyperstable variant, hydrolase, calcium, endonuclease, metal-binding, secreted, zymogen
Biological source	Staphylococcus aureus
Cellular location	Nuclease A: Secreted. Nuclease B: Membrane: P00644
Total number of polymer chains	1
Total formula weight	17220.50
Authors	Harms, M.J.,Schlessman, J.L.,Sue, G.R.,Garcia-Moreno, E.B. (deposition date: 2008-05-19, release date: 2008-11-04, Last modification date: 2024-02-21)
Primary citation	Harms, M.J.,Castaneda, C.A.,Schlessman, J.L.,Sue, G.R.,Isom, D.G.,Cannon, B.R.,Garcia-Moreno, E.B. The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors. J.Mol.Biol., 389:34-47, 2009 Cited by PubMed: 19324049 DOI: 10.1016/j.jmb.2009.03.039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation