3CXF
Crystal structure of transthyretin variant Y114H
Summary for 3CXF
Entry DOI | 10.2210/pdb3cxf/pdb |
Related | 1F41 2G4E 2NOY 3BSZ 3BT0 |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | ttr, amyloid fibrils, point mutation, transport protein, amyloid, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hormone, polymorphism, polyneuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27504.67 |
Authors | Cendron, L.,Zanotti, G.,Folli, C.,Alfieri, B.,Pasquato, N.,Berni, R. (deposition date: 2008-04-24, release date: 2009-04-07, Last modification date: 2023-11-01) |
Primary citation | Zanotti, G.,Folli, C.,Cendron, L.,Alfieri, B.,Nishida, S.K.,Gliubich, F.,Pasquato, N.,Negro, A.,Berni, R. Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein. Febs J., 275:5841-5854, 2008 Cited by PubMed: 19021760DOI: 10.1111/j.1742-4658.2008.06705.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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