3CUK
Crystal structure of human D-amino acid oxidase: bound to an inhibitor
Summary for 3CUK
Entry DOI | 10.2210/pdb3cuk/pdb |
Descriptor | D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 4H-furo[3,2-b]pyrrole-5-carboxylic acid, ... (4 entities in total) |
Functional Keywords | oxidoreductase, alpha-beta-alpha motif, flavin containing proteinalpha-beta-alpha motif, flavin containing protein, fad, flavoprotein, peroxisome |
Biological source | Homo sapiens |
Cellular location | Peroxisome: P14920 |
Total number of polymer chains | 4 |
Total formula weight | 161830.32 |
Authors | Prasad, S.,Munshi, S. (deposition date: 2008-04-16, release date: 2008-07-22, Last modification date: 2023-08-30) |
Primary citation | Sparey, T.,Abeywickrema, P.,Almond, S.,Brandon, N.,Byrne, N.,Campbell, A.,Hutson, P.H.,Jacobson, M.,Jones, B.,Munshi, S.,Pascarella, D.,Pike, A.,Prasad, G.S.,Sachs, N.,Sakatis, M.,Sardana, V.,Venkatraman, S.,Young, M.B. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg.Med.Chem.Lett., 18:3386-3391, 2008 Cited by PubMed: 18455394DOI: 10.1016/j.bmcl.2008.04.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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