3CQA
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
Summary for 3CQA
| Entry DOI | 10.2210/pdb3cqa/pdb |
| Descriptor | Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | crystal packing, acetylation, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, hormone |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted: P05230 |
| Total number of polymer chains | 2 |
| Total formula weight | 32872.80 |
| Authors | Meher, A.K.,Honjo, E.,Kuroki, R.,Lee, J.,Somasundaram, T.,Blaber, M. (deposition date: 2008-04-02, release date: 2009-04-07, Last modification date: 2023-08-30) |
| Primary citation | Meher, A.K.,Blaber, S.I.,Lee, J.,Honjo, E.,Kuroki, R.,Blaber, M. Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65:1136-1140, 2009 Cited by PubMed: 19923735DOI: 10.1107/S1744309109036987 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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