3CJK

Crystal structure of the adduct HAH1-Cd(II)-MNK1.

Summary for 3CJK

• Entry DOI: 10.2210/pdb3cjk/pdb
• Related: 1FE0 1KVI
• Descriptor: Copper transport protein ATOX1, Copper-transporting ATPase 1, CADMIUM ION, ... (4 entities in total)
• Functional Keywords: hah1; atp7a; atp7b; menkes disease; metal homeostasis, chaperone, copper, copper transport, ion transport, metal-binding, transport, alternative splicing, atp-binding, cytoplasm, disease mutation, endoplasmic reticulum, glycoprotein, golgi apparatus, hydrolase, magnesium, membrane, nucleotide-binding, phosphoprotein, polymorphism, transmembrane, metal transport-hydrolase complex, metal transport/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Isoform 3: Cytoplasm, cytosol (Probable). Isoform 5: Endoplasmic reticulum: Q04656
• Total number of polymer chains: 2
• Total formula weight: 15824.46

Authors

Banci, L.,Bertini, I.,Calderone, V.,Felli, I.,Della-Malva, N.,Pavelkova, A.,Rosato, A. (deposition date: 2008-03-13, release date: 2008-12-30, Last modification date: 2023-08-30)

• Primary citation: Banci, L.,Bertini, I.,Calderone, V.,Della-Malva, N.,Felli, I.C.,Neri, S.,Pavelkova, A.,Rosato, A.; Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces.; Biochem.J., 422:37-42, 2009; PubMed: 19453293; DOI: 10.1042/BJ20090422

Experimental method

X-RAY DIFFRACTION (1.8 Å)