3C9W
Crystal Structure of ERK-2 with hypothemycin covalently bound
Summary for 3C9W
Entry DOI | 10.2210/pdb3c9w/pdb |
Related | 1ERK 2E14 |
Descriptor | Mitogen-activated protein kinase 1, (1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione (3 entities in total) |
Functional Keywords | erk, acetylation, atp-binding, cell cycle, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Cytoplasm, cytoskeleton, spindle : P63086 |
Total number of polymer chains | 2 |
Total formula weight | 83155.46 |
Authors | Rosenfeld, R.J. (deposition date: 2008-02-18, release date: 2008-07-08, Last modification date: 2023-11-01) |
Primary citation | Rastelli, G.,Rosenfeld, R.,Reid, R.,Santi, D.V. Molecular modeling and crystal structure of ERK2-hypothemycin complexes J.Struct.Biol., 164:18-23, 2008 Cited by PubMed: 18571434DOI: 10.1016/j.jsb.2008.05.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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