3C9W
Crystal Structure of ERK-2 with hypothemycin covalently bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase 1 | polymer | 357 | 41199.4 | 2 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (Rat) | Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, p42-MAPK, ERT1 |
| 2 | C, D (A, B) | (1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione | non-polymer | 378.4 | 2 | Chemie (HMY) PubChem (21776315) PubChem (21776316) PubChem (22871211) PubChem (23281075) PubChem (53315137) PubChem (73075931) PubChem (73265221) PubChem (9929643) PubChem (10249057) PubChem (10270986) PubChem (11728572) PubChem (101511149) PubChem (131676399) PubChem (154584061) PubChem (163059289) PubChem (163059290) PubChem (168972843) PubChem (168972845) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82398.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 756.7 | |
| All* | Total formula weight | 83155.5 |
