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3C4M

Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)

Summary for 3C4M
Entry DOI10.2210/pdb3c4m/pdb
Related PRD IDPRD_900001
DescriptorFusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywordsparathyroid hormone, g-protein-coupled receptor, sugar transport, transport, cleavage on pair of basic residues, disease mutation, secreted, dwarfism, glycoprotein, membrane, receptor, transducer, transmembrane, membrane protein
Biological sourceEscherichia coli (, human)
More
Total number of polymer chains4
Total formula weight126372.39
Authors
Pioszak, A.A.,Xu, H.E. (deposition date: 2008-01-30, release date: 2008-04-08, Last modification date: 2023-08-30)
Primary citationPioszak, A.A.,Xu, H.E.
Molecular recognition of parathyroid hormone by its G protein-coupled receptor.
Proc.Natl.Acad.Sci.Usa, 105:5034-5039, 2008
Cited by
PubMed: 18375760
DOI: 10.1073/pnas.0801027105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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