3BPL

Crystal structure of the IL4-IL4R-Common Gamma ternary complex

Summary for 3BPL

Entry DOI	10.2210/pdb3bpl/pdb
Related	3BPN 3BPO
Descriptor	Interleukin-4, Interleukin-4 receptor alpha chain, Cytokine receptor common gamma chain, ... (7 entities in total)
Functional Keywords	il4, il13, receptor, cytokine, b-cell activation, glycoprotein, growth factor, secreted, immune response, membrane, phosphoprotein, transmembrane, disease mutation, host-virus interaction, scid, cytokine-receptor complex, cytokine-cytokine receptor complex, cytokine/cytokine receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	64030.83
Authors	Garcia, K.C. (deposition date: 2007-12-18, release date: 2008-02-05, Last modification date: 2021-10-20)
Primary citation	Laporte, S.L.,Juo, Z.S.,Vaclavikova, J.,Colf, L.A.,Qi, X.,Heller, N.M.,Keegan, A.D.,Garcia, K.C. Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System. Cell(Cambridge,Mass.), 132:259-272, 2008 Cited by PubMed: 18243101 DOI: 10.1016/j.cell.2007.12.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.93 Å)

Structure validation