3BN9
Crystal Structure of MT-SP1 in complex with Fab Inhibitor E2
Summary for 3BN9
Entry DOI | 10.2210/pdb3bn9/pdb |
Related | 3BN5 |
Descriptor | Membrane-type serine protease 1, E2 Fab Light Chain, E2 Fab Heavy Chain, ... (6 entities in total) |
Functional Keywords | antibody-protease complex, protein-protein complex, enzyme-inhibitor complex, disease mutation, glycoprotein, hydrolase, membrane, polymorphism, serine protease, signal-anchor, transmembrane |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane ; Single-pass type II membrane protein : Q9Y5Y6 |
Total number of polymer chains | 6 |
Total formula weight | 154648.53 |
Authors | Farady, C.J.,Schneider, E.L.,Egea, P.F.,Goetz, D.H.,Craik, C.S. (deposition date: 2007-12-13, release date: 2008-09-09, Last modification date: 2023-08-30) |
Primary citation | Farady, C.J.,Egea, P.F.,Schneider, E.L.,Darragh, M.R.,Craik, C.S. Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition J.Mol.Biol., 380:351-360, 2008 Cited by PubMed: 18514224DOI: 10.1016/j.jmb.2008.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.173 Å) |
Structure validation
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