3BKB

Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)

Summary for 3BKB

Entry DOI	10.2210/pdb3bkb/pdb
Descriptor	Proto-oncogene tyrosine-protein kinase Fes/Fps, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	fes, v-fes, fujinami, avian sarcoma, viral, oncogene, feline sarcoma virus, sgc, structural genomics consortium, atp-binding, kinase, nucleotide-binding, phosphoprotein, proto-oncogene, sh2 domain, transferase, tyrosine-protein kinase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	44009.31
Authors	Filippakopoulos, P.,Salah, E.,Fedorov, O.,Cooper, C.,Ugochukwu, E.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-12-06, release date: 2007-12-25, Last modification date: 2023-08-30)
Primary citation	Filippakopoulos, P.,Kofler, M.,Hantschel, O.,Gish, G.D.,Grebien, F.,Salah, E.,Neudecker, P.,Kay, L.E.,Turk, B.E.,Superti-Furga, G.,Pawson, T.,Knapp, S. Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134:793-803, 2008 Cited by PubMed: 18775312 DOI: 10.1016/j.cell.2008.07.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation