3BHE
HIV-1 protease in complex with a three armed pyrrolidine derivative
Summary for 3BHE
Entry DOI | 10.2210/pdb3bhe/pdb |
Descriptor | Protease, N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide (3 entities in total) |
Functional Keywords | protein-ligand complex, hydrolase |
Biological source | Human immunodeficiency virus type 1 (BRU ISOLATE) |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367 |
Total number of polymer chains | 2 |
Total formula weight | 22024.09 |
Authors | Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G. (deposition date: 2007-11-28, release date: 2008-12-09, Last modification date: 2023-11-01) |
Primary citation | Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G. HIV-1 protease in complex with a three armed pyrrolidine derivative To be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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