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3BH9

Crystal Structure of RTY Phosphopeptide Bound to Human Class I MHC HLA-A2

Summary for 3BH9
Entry DOI10.2210/pdb3bh9/pdb
Related3BGM 3BH8 3BHA 3BHB
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, decameric peptide from Protein POF1B, ... (6 entities in total)
Functional Keywordsphosphoserine, phosphopeptide, mhc, hla-a2, anchor residue, tumor antigen, glycoprotein, host-virus interaction, immune response, mhc i, polymorphism, transmembrane, ubl conjugation, immunoglobulin domain, phosphoprotein, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted . Note=(Microbial infection) In the presence of M: P61769
Cell junction, tight junction : Q8WVV4
Total number of polymer chains3
Total formula weight45115.00
Authors
Mohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E. (deposition date: 2007-11-28, release date: 2008-10-21, Last modification date: 2017-10-11)
Primary citationMohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E.
Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9:1236-1243, 2008
Cited by
PubMed: 18836451
DOI: 10.1038/ni.1660
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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