3BH8
Crystal Structure of RQA_M Phosphopeptide Bound to HUMAN Class I MHC HLA-A2
Summary for 3BH8
Entry DOI | 10.2210/pdb3bh8/pdb |
Related | 3BGM 3BH9 3BHA 3BHB |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, decameric peptide from Lymphocyte-specific protein 1, ... (5 entities in total) |
Functional Keywords | phosphoserine, phosphopeptide, mhc, hla-a2, anchor residue, tumor antigen, glycoprotein, host-virus interaction, immune response, mhc i, polymorphism, transmembrane, ubl conjugation, immunoglobulin domain, phosphoprotein, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Cell membrane; Peripheral membrane protein; Cytoplasmic side: P33241 |
Total number of polymer chains | 3 |
Total formula weight | 44940.87 |
Authors | Mohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E. (deposition date: 2007-11-28, release date: 2008-10-21, Last modification date: 2011-07-13) |
Primary citation | Mohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self Nat.Immunol., 9:1236-1243, 2008 Cited by PubMed: 18836451DOI: 10.1038/ni.1660 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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