3AVM

Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site

Summary for 3AVM

Entry DOI	10.2210/pdb3avm/pdb
Related	3AV9 3AVA 3AVB 3AVC 3AVF 3AVG 3AVH 3AVI 3AVJ 3AVK 3AVL 3AVN
Related PRD ID	PRD_000826
Descriptor	Integrase, LEDGF peptide, SULFATE ION, ... (6 entities in total)
Functional Keywords	protein-protein interactions, hiv, recombination-inhibitor complex, recombination/inhibitor
Biological source	Human immunodeficiency virus type 1 (HIV-1) More
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
Total number of polymer chains	4
Total formula weight	43093.08
Authors	Peat, T.S.,Deadman, J.J.,Newman, J.,Rhodes, D.I. (deposition date: 2011-03-05, release date: 2012-01-18, Last modification date: 2013-06-19)
Primary citation	Rhodes, D.I.,Peat, T.S.,Vandegraaff, N.,Jeevarajah, D.,Newman, J.,Martyn, J.,Coates, J.A.,Ede, N.J.,Rea, P.,Deadman, J.J. Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12:2311-2315, 2011 Cited by PubMed: 21850718 DOI: 10.1002/cbic.201100350 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation