3AUN
Crystal structure of the rat vitamin D receptor ligand binding domain complexed with YR335 and a synthetic peptide containing the NR2 box of DRIP 205
Summary for 3AUN
Entry DOI | 10.2210/pdb3aun/pdb |
Related | 2ZFX |
Descriptor | Vitamin D3 receptor, DRIP 205 NR2 box peptide, (2R)-2-{4-[3-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)pentan-3-yl]-2-methylphenoxy}butane-1,4-diol, ... (4 entities in total) |
Functional Keywords | binding sites, biphenyl compounds, protein binding, tertiary, rats, receptors, calcitriol, vitamin d, transcription |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Nucleus: P13053 Q15648 |
Total number of polymer chains | 2 |
Total formula weight | 32099.05 |
Authors | Kakuda, S.,Takimoto-Kamimura, M. (deposition date: 2011-02-10, release date: 2012-02-15, Last modification date: 2023-11-01) |
Primary citation | Demizu, Y.,Takahashi, T.,Kaneko, F.,Sato, Y.,Okuda, H.,Ochiai, E.,Horie, K.,Takagi, K.,Kakuda, S.,Takimoto-Kamimura, M.,Kurihara, M. Design, synthesis and X-ray crystallographic study of new nonsecosteroidal vitamin D receptor ligands Bioorg.Med.Chem.Lett., 21:6104-6107, 2011 Cited by PubMed: 21889334DOI: 10.1016/j.bmcl.2011.08.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
Download full validation report