3AUN
Crystal structure of the rat vitamin D receptor ligand binding domain complexed with YR335 and a synthetic peptide containing the NR2 box of DRIP 205
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin D3 receptor | polymer | 265 | 30055.5 | 1 | UniProt (P13053) Pfam (PF00104) | Rattus norvegicus (rat) | VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| 2 | B (B) | DRIP 205 NR2 box peptide | polymer | 13 | 1570.9 | 1 | UniProt (Q15648) | synthetic construct | Peroxisome proliferator-activated receptor-binding protein, Vitamin D receptor-interacting protein complex component DRIP205, Mediator of RNA polymerase II transcription subunit 1 |
| 3 | C (A) | (2R)-2-{4-[3-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)pentan-3-yl]-2-methylphenoxy}butane-1,4-diol | non-polymer | 472.7 | 1 | Chemie (YR4) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A: 116 - 164 (UniProt: P13053)
A: 212 - 423 (UniProt: P13053)
| PDB | External Database | Details |
|---|---|---|
| Gly 112 | - | expression tag |
| Ser 113 | - | expression tag |
| His 114 | - | expression tag |
| Met 115 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31626.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 472.7 | |
| All* | Total formula weight | 32099.1 |
