3ABA
Crystal structure of CYP105P1 in complex with filipin I
Summary for 3ABA
Entry DOI | 10.2210/pdb3aba/pdb |
Related | 3ABB 3E5J 3E5K 3E5L |
Descriptor | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,28R)-3-hexyl-4,6,8,10,12,14,16-heptahydroxy-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one, ... (5 entities in total) |
Functional Keywords | p450, oxidoreductase, heme, monooxygenase, macrolide, filipin, iron, metal-binding, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic |
Biological source | Streptomyces avermitilis |
Total number of polymer chains | 1 |
Total formula weight | 45957.00 |
Authors | Xu, L.H.,Fushinobu, S.,Takamatsu, S.,Wakagi, T.,Ikeda, H.,Shoun, H. (deposition date: 2009-12-04, release date: 2010-04-07, Last modification date: 2023-11-01) |
Primary citation | Xu, L.H.,Fushinobu, S.,Takamatsu, S.,Wakagi, T.,Ikeda, H.,Shoun, H. Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis J.Biol.Chem., 285:16844-16853, 2010 Cited by PubMed: 20375018DOI: 10.1074/jbc.M109.092460 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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