38KI

Cx46 Dual-Channel Assembly - Offset

Summary for 38KI

• Entry DOI: 10.2210/pdb38ki/pdb
• EMDB information: 78875
• Descriptor: Gap junction alpha-3 protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
• Functional Keywords: connexin, gap junction, lipids, large-pore ion channel, membrane protein
• Biological source: Bos taurus (domestic cattle)
• Total number of polymer chains: 24
• Total formula weight: 689988.88

Authors

Garrels, C.S.,Reichow, S.L. (deposition date: 2026-08-31, release date: 2026-10-28)

• Primary citation: Garrels, C.S.,Myers, J.B.,Souza, S.A.,Jarodsky, J.M.,Reichow, S.L.; Lipids intercalate and mediate multi-channel assemblies of connexin-46/50 gap junctions; Nat Commun, 2026; DOI: 10.1038/s41467-026-78903-0

Experimental method

ELECTRON MICROSCOPY (3.43 Å)