38HK

Crystal structure of the transpeptidase domain of a Y422F mutant of PBP2 from Neisseria gonorrhoeae strain H041

Summary for 38HK

• Entry DOI: 10.2210/pdb38hk/pdb
• Descriptor: Probable peptidoglycan D,D-transpeptidase PenA (2 entities in total)
• Functional Keywords: neisseria gonorrhoeae, penicillin-binding protein 2, cephalosporin resistance, site-directed mutant, ligase
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 1
• Total formula weight: 35345.50

Authors

Bala, S.,Stratton, C.M.,Davies, C. (deposition date: 2026-08-27, release date: 2026-09-16)

• Primary citation: Stratton, C.M.,Bala, S.,Bivins, M.M.,Nicholas, R.A.,Davies, C.; Energetic coupling of an active site residue in penicillin-binding protein 2 from Neisseria gonorrhoeae with a resistance-associated conformational switch in the beta3-beta4 loop; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.603 Å)