38FX

CYP3A4 bound to azamulin

Summary for 38FX

• Entry DOI: 10.2210/pdb38fx/pdb
• EMDB information: 78783
• Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl [(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]acetate (3 entities in total)
• Functional Keywords: inhibited complex, cytochrome p450, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 170558.84

Authors

Orta, A.K.,Fraser, J.S. (deposition date: 2026-08-24, release date: 2026-09-30)

• Primary citation: Orta, A.K.,Fraser, J.S.; Structural analysis of CYP3A4 inhibition by Cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.21 Å)