36YD

S. aureus DNA Gyrase in complex with OSUAB-0276 and DNA

This is a non-PDB format compatible entry.

Summary for 36YD

• Entry DOI: 10.2210/pdb36yd/pdb
• EMDB information: 77961
• Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), DNA gyrase subunit B,DNA gyrase subunit A, (6P)-6-(1-{1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]piperidin-4-yl}-1H-1,2,3-triazol-4-yl)-2H-1,4-benzoxazin-3(4H)-one, ... (4 entities in total)
• Functional Keywords: topoisomerase, nbti, dna binding protein
• Biological source: Staphylococcus aureus subsp. aureus N315; More
• Total number of polymer chains: 4
• Total formula weight: 169217.42

Authors

Wheat, C.T.,Bell, C.E. (deposition date: 2026-07-06, release date: 2026-10-07)

• Primary citation: Cassel, S.R.,Powell, J.W.,Wheat, C.T.,Tomaszewski, A.J.,Dellos-Nolan, S.,Landgraf, A.D.,Sham, M.P.,Carvajal-Moreno, J.,Lu, Y.,Chen, A.,Bell, C.E.,Wozniak, D.J.,Yalowich, J.C.,Mitton-Fry, M.J.; OSUAB-0276, a novel bacterial topoisomerase inhibitor (NBTI) with dual activity against bacterial and human type II topoisomerases; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.68 Å)