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36MP

Covalent molecular glue EM12-FS in complex with CRBN/DDB1 and NTAQ1

This is a non-PDB format compatible entry.
Summary for 36MP
Entry DOI10.2210/pdb36mp/pdb
EMDB information77682
DescriptorDNA damage-binding protein 1, Protein cereblon, Protein N-terminal glutamine amidohydrolase, ... (4 entities in total)
Functional Keywordsglue, complex, covalent, degradation, ligase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight174035.44
Authors
de la Pena, A.H.,Cruite, J.T.,Jones, L.H. (deposition date: 2026-06-18, release date: 2026-10-28)
Primary citationde la Pena, A.H.,Cruite, J.T.,Che, J.,Matyskiela, M.E.,Chamberlain, P.P.,Fischer, E.S.,Jones, L.H.
Structure of the NTAQ1-EM12-FS-CRBN-DDB1 complex
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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PDB entries from 2026-11-04

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