36JC

Crystal structure of Yck2 from Candida albicans in complex with kinase inhibitor YK-1-55: 3-(2-aminopyridin-4-yl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-6-carbonitrile

This is a non-PDB format compatible entry.

Summary for 36JC

• Entry DOI: 10.2210/pdb36jc/pdb
• Descriptor: Serine/threonine protein kinase YCK2, (3M,8S)-3-(2-aminopyridin-4-yl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-6-carbonitrile, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: casein kinase 1, yck2, kinase, kinase inhibitor, structural genomics, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, transferase, transferase-transferase inhibitor complex, center for structural biology of infectious diseases, csbid
• Biological source: Candida albicans
• Total number of polymer chains: 1
• Total formula weight: 35492.54

Authors

Stogios, P.J.,Lemak, S.,Williams, A.,Prive, G.G.,Cowen, L.E.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID) (deposition date: 2026-06-13, release date: 2026-08-19)

• Primary citation: Stogios, P.J.; Crystal structure of Yck2 from Candida albicans in complex with kinase inhibitor YK-1-55: 3-(2-aminopyridin-4-yl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-6-carbonitrile; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)