36AC

Ternary complex between CHD4-C1bC2ab, GATAD2ACR2, and CDK2AP1

Summary for 36AC

Entry DOI	10.2210/pdb36ac/pdb
Descriptor	Cyclin-dependent kinase 2-associated protein 1, Chromodomain-helicase-DNA-binding protein 4, Transcriptional repressor p66-alpha, ... (5 entities in total)
Functional Keywords	chromatin remodeling complex, dna binding, nurd, gene regulation
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	65951.96
Authors	Williams, D.C.,Li, T.,McGinty, R.K. (deposition date: 2026-05-27, release date: 2026-10-28)
Primary citation	Williams, D.C.J.,Ren, J.,Li, T.,Pelton, J.M.,Dedakia, D.,Novy, B.,Popov, K.I.,McGinty, R.K.,Ginder, G.D.,Bowers, A.A. Macrocycle Screening against the C-Terminal Region of CHD4 Uncovers Its Role as an Interaction Hub in the Formation of the Nucleosome Remodeling and Deacetylase Complex J.Am.Chem.Soc., 2026 Cited by DOI: 10.1021/jacs.6c11754 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation