360D
STRUCTURE OF 2,5-BIS{[4-(N-ETHYLAMIDINO)PHENYL]}FURAN COMPLEXED TO 5'-D(CPGPCPGPAPAPTPTPCPGPCPG)-3'. A MINOR GROOVE DRUG COMPLEX, SHOWING PATTERNS OF GROOVE HYDRATION
Summary for 360D
Entry DOI | 10.2210/pdb360d/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, N,N'-(furan-2,5-diylbis{benzene-4,1-diyl[(Z)-aminomethylylidene]})diethanaminium, ... (4 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, dna |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 7713.56 |
Authors | Guerri, A.,Simpson, I.J.,Neidle, S. (deposition date: 1997-10-29, release date: 1998-07-16, Last modification date: 2023-08-02) |
Primary citation | Guerri, A.,Simpson, I.J.,Neidle, S. Visualisation of extensive water ribbons and networks in a DNA minor-groove drug complex. Nucleic Acids Res., 26:2873-2878, 1998 Cited by PubMed: 9611230DOI: 10.1093/nar/26.12.2873 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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