35VC

cAMP-bound WT SthK in 4:1 DOPC:POPA nanodiscs

Summary for 35VC

• Entry DOI: 10.2210/pdb35vc/pdb
• EMDB information: 77218
• Descriptor: Putative transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total)
• Functional Keywords: ion channel, lipid modulation, phosphatidic acid, allostery, ligand binding, membrane protein
• Biological source: Winmispira thermophila DSM 6578
• Total number of polymer chains: 4
• Total formula weight: 224233.26

Authors

Newton, A.N.,Kuforiji, A.E.,Schmidpeter, P.A. (deposition date: 2026-05-19, release date: 2026-10-14)

• Primary citation: Newton, A.J.,Kuforiji, A.E.,Schmidpeter, P.A.; Concentration-dependent switching between ligand-like and solvent-like lipid regulation in a model ion channel; Nat Commun, 2026

Experimental method

ELECTRON MICROSCOPY (2.94 Å)